Synthesis of Strained Heterobicycles from Alkynes and Heterocumulenes

DOI: 10.1021/jo00349a017

Source and publish data:

Journal of Organic Chemistry p. 1909 - 1915 (1982)

Update date:2022-08-03

Topics:

Authors:

Hogeveen, H.

Kingma, R. F.

Kok, D. M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00349a017

A one-pot synthesis of strained heterobicycles such as 2-thia(or 2-aza)-3-iminobicyclo<2.2.0>hex-5-enes and 2-thia-3-azabicyclo<4.2.0>oct-7-ene 2-oxides from alkynes, aluminum halides, and heterocumulenes (isothiocyanates, carbodiimides, N-sulfinylaniline) is described.The thermal and acid-promoted reactions of the permethylated 2-thia-3-iminobicyclo<2.2.0>hex-5-ene 2 to monocyclic isomeres are reported.

Full text of DOI:10.1021/jo00349a017

Products guided by the article

Product name:1,4,5,6-tetramethyl-2-thia-3-(phenylimino)bicyclo<2.2.0>hex-5-ene

Cas No:81045-14-9

R&D Labs maybe for 81045-14-9

Yangzhou Siyu Chemical Co.,Ltd.

Contact:+86-514-87325867 13358126196

Address:Room 620 Exposition Pavilion，No. 98 Huaihai Road,Guangling District，Yangzhou City, Jiangsu Province
Acros Pharmatech Limited

website:http://www.acrospharmatech.com

Contact:+1-3234804688

Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
Shanghai better-in Medical Technology Co.,LTD.

Contact:+86-21-38921049

Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Shreeji pharma international

Contact:0091-265-2313036

Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA

Relevant to this article

Stereoselective synthesis of tri- and tetrasubstituted α,β-unsaturated esters via copper-catalyzed coupling of enol triflates of β-ketoesters with Grignard-based zinc ate complexes

Doi:10.1055/s-2001-17479
(2001)
Effect of the Oxidation State of the Sulfur Atom on the Exchange Interaction between Two Triplet Carbene Units through Diphenyl Sulfide p,p'-Diyl Couplers

Doi:10.1246/cl.1995.1085
(1995)
Synthesis of N-{4-[2-(2-amino-5,6-dihydro-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-6-y l)-ethyl]benzoyl}-L-glutamic acid: A ring-contracted analogue of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid

Doi:10.1021/jo951471k
(1996)
Enantiocontrolled construction of sistodiolynne, an unusual polyketide from the wood-decay fungus Sistrema raduloides

Doi:10.1039/a700186j
(1997)
Doi:10.1021/jo01274a020
(1968)
Synthesis and glycosaminoglycan priming activity of three disaccharides related to the linkage region tetrasaccharide of proteoglycans

Doi:10.1016/0008-6215(95)00304-5
(1995)

Article Doi