SYNTHESIS OF PEPTIDES CONTAINING HYDROXYAMINO ACIDS BY THE MIXED ANHYDRIDE METHOD WITHOUT PROTECTING THE HYDROXYL FUNCTIONS

DOI: 10.1246/cl.1982.45

Source and publish data:

Chemistry Letters p. 45 - 48 (1982)

Update date:2022-08-05

Topics: Purification and characterization Coupling Fmoc Deprotection Cleavage and Deprotection

Authors:

Ueki, Masaaki

Inazu, Toshiyuki

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Article abstract of DOI:10.1246/cl.1982.45

Dimethylphosphinothioyl (Mpt) mixed anhydrides of N-protected amino acids were found to be isolatably stable and useful for the synthesis of hydroxyamino acid containing peptides without protecting the side-chain hydroxyl functions.They were applied for t

Full text of DOI:10.1246/cl.1982.45

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