DUNAWITHANINES A AND B, THE FIRST WITHANOLIDE GLYCOSIDES FROM DUNALIA AUSTRALIS

Article abstract of DOI:10.1016/S0031-9422(00)80538-5

Withanolide D, 7β-acetoxy-withanolide D and two new withanolide glycosides, named dunawithanines A and B, were isolated from Dunalia australis.From physical data and chemical transformations, the structures of the new compounds were determined as (20R,22R)-O(3)-<2',3'-di-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl>-3β,20-dihydroxy-1α-acetoxy-witha-5,24-dienolide and the corresponding O(3)-<β-D-glucopyranosyl(1'->x)-β-D-glucopyranosyl> compound, representing the first withanolide glycosides found in the plant kingdom. - Key Word Index: Dunalia australis; Solanaceae; withanolide glycosides; steroidal lactones; dunawithanines A and B.