Journal of Organic Chemistry p. 3274 - 3278 (1982)
Update date:2022-08-04
Topics:
Janssen, Cornelus G. M.
Godefroi, Erik F.
An efficient three-step strategy into resin acid type systems III and their cis isomers VI is presented.As illustrated by five exampels, the method involves geranylation of sulfones 7a-c and nerylation of 7a,b to 8a-c and 9a,b, respectively.Subsequent FSO3H-SO2-promoted polyene cyclizations proceed stereospecifically and with asymmetric induction to produce epimeric diastereomers 10a-c/11a-c and 12a,b/13a,b in 60:40 and 70:30 ratios.Each epimeric set undergoes Dibal-H-mediated detosylation to provide diastereomeric compounds 15-19 in high yields.
View MoreSHUNYUANSHENG BIO-PHARMTECH CO., LTD
website:https://www.whsysbio.com
Contact:--
Address:Building 13, Liandong U Valley-Wuhan Economic Innovation Valley, No. 259, Xingsan Road, Shamao Street, Hannan District, Wuhan City, Hubei Province
Contact:86-10-62983737; +86-10-51287608
Address:4/F Building C, 2 Shangdi Xinxi Road
Contact:
Address:
Jinan Hongfangde Pharmatech Co.LTD
Contact:0531-88870908
Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Synochem Ingredients Corp., Ltd.
Contact:+86-512-5636 2180
Address:Zhangjiagang Free Trade Zone
Doi:10.1016/S0040-4039(00)86862-8
(1982)Doi:10.1016/j.bmcl.2017.05.025
(2017)Doi:10.1135/cccc19820984
(1982)Doi:10.1248/cpb.30.428
(1982)Doi:10.1021/jo00140a048
(1982)Doi:10.1016/j.molstruc.2014.04.032
(2014)
