Bulletin of the Chemical Society of Japan p. 1826 - 1831 (1983)
Update date:2022-08-04
Topics:
Tanabe
Yamauchi
Kinoshita
Action of trimethyl phosphate on thymidine 5 prime -phosphate, deoxycytidine 5 prime -phosphate, deoxyadenosine 5 prime -phosphate, and deoxyguanosine 5 prime -phosphate at 37-60 degree C, and pH 7-10 gave their methyl esters and base-methylated derivatives. Esterification took place in all deoxyribonucleotides to the almost same extent and its rate was enhanced by the reaction temperature, while being independent of pH in the range 7-10. On the other hand, methylation of the base moieties was affected by both the reaction temperature and pH of the reaction medium.
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Doi:10.1007/BF00901294
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(1982)Doi:10.1016/0040-4020(82)85046-1
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(1988)
