Journal of Medicinal Chemistry p. 2157 - 2162 (1990)
Update date:2022-08-03
Topics:
Gerhart
Higgins
Tardif
Ducep
2-(4-Amino-4-carboxybutyl)aziridine-2-carboxylic acid (3) (aziridino-DAP) was identified as the product of spontaneous hydrolysis of α-(halomethyl)diaminopimelic acids (α-halomethyl-DAPs) 2a-c. Under physiological conditions, 3 is an extremely potent irre
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