Role of the hydrophobic moiety of tumor promoters. Synthesis and activity of 9-alkylated benzolactams

DOI: 10.1248/cpb.44.1138

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1138 - 1140 (1996)

Update date:2022-08-03

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Authors:

Endo, Yasuyuki

Yamaguchi, Mitsuhiro

Hirano, Masaaki

Shudo, Koichi

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Article abstract of DOI:10.1248/cpb.44.1138

(-)-Benzolactam-V8-310 reproduces the active conformation and biological activity of teleocidins. Various sizes and shapes of alkyl groups on aromatic nucleus of BL-V8 were synthesized as optically pure forms. Structure-activity results indicate that hydr

Full text of DOI:10.1248/cpb.44.1138

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