Total synthesis of zizaane sesquiterpenes: (-)-khusimone, (+)-zizanoic acid, and (-)-epizizanoic acid

Article abstract of DOI:10.1139/v82-161

Three sesquiterpenes of the zizaane family, khusimone (1), epizizanoic acid (3), and zizanoic acid (2) have been synthesized in optically active form from the ammonium salt of (-)-l-10-camphorsulfonic acid in sixteen, nineteen, and twenty steps respectively.