Tetrahedron Letters p. 6991 - 6994 (1992)
Update date:2022-08-03
Topics:
Murahashi, Shun-Ichi
Naota, Takeshi
Miyaguchi, Noriko
Nakato, Takeshi
α-Methoxylation of tertiary amines can be performed by the ruthenium-catalyzed oxidation of tertiary amines with hydrogen peroxide in the presence of methanol. The reaction provides an efficient method for selective N-demethylation of tertiary methylamines and construction of quinoline skeletons.
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(1982)Doi:10.1021/jo00144a013
(1982)Doi:10.1021/jo070389+
(2007)Doi:10.1039/jr9450000234
(1945)Doi:10.1016/0040-4020(82)80068-9
(1982)Doi:10.1021/jo00143a030
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