Synthesis of 2-ethynylaziridines

Article abstract of DOI:10.1007/BF00526085

2-Ethynyl-substituted aziridines were obtained by the reaction of acetylenic β-amino and β-azido alcohols with triphenylphosphine and carbon tetrachloride in the presence of triethylamine. The cycloaddition of carbenes and diazomethane to an acetylenic imine was investigated. 2-Ethynylaziridines were obtained in the case of carbonylalkoxycarbenes. The regioselectivity of the cycloaddition of carbenes to an acetylenic imine is demonstrated.