1,2-Dihydropyrido[3,4-b]pyrazines: Structure-activity relationships

DOI: 10.1021/jm00355a018

Source and publish data:

Journal of Medicinal Chemistry p. 91 - 95 (1983)

Update date:2022-09-26

Topics:

Authors:

Temple Jr.

Wheeler Wheeler

Elliott Elliott

Rose Rose

Comber Comber

Montgomery

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Article abstract of DOI:10.1021/jm00355a018

Certain derivatives containing the 1,2-dihydropyrido[3,4-b]pyrazine (1-deaza-7,8-dihydropteridine) ring system are active against experimental neoplasms in mice. The mechanism of action of these agents has r539w1 =4-amino-1-deaza-7,8-dihydro-6-[(N-methyla

Full text of DOI:10.1021/jm00355a018

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