Practical synthetic approaches to intermediates for the preparations of the novel O-sulfonated-N-hydroxy-2-azetidinone antibiotics

DOI: 10.1016/S0040-4020(01)92150-7

Source and publish data:

Tetrahedron p. 2571 - 2575 (1983)

Update date:2022-09-26

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Authors:

Miller Miller

Biswas Biswas

Krook Krook

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Article abstract of DOI:10.1016/S0040-4020(01)92150-7

A practical synthesis of intermediates useful for the preparation of a variety of monocyclic β-lactam antibiotics is described. Hydroxaminolysis of N-protected serine esters provided the hydroxamic acids 10. Acylation followed by cyclization yielded the β

Full text of DOI:10.1016/S0040-4020(01)92150-7

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