Tetrahedron Letters p. 2145 - 2148 (1991)
Update date:2022-08-05
Topics:
Murahashi, Shun-Ichi
Saito, Takao
Naota, Takeshi
Osmium-catalyzed oxidation of β-lactams with peroxides in acetic acid gives the corresponding 4-acetoxy β-lactams, which are versatile synthetic intermediate of carbapenem antibiotics, in good to excellent yields.
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Doi:10.1039/c6md00243a
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