On the Stereochemistry of Bisoxiranes of Vitamin D3 4-Phenyl-triazoline-3,5-dione-Adducts: X-Ray Structure Analysis of One of Their Benzoyl Derivatives

Article abstract of DOI:10.1007/BF00809300

Upon complete epoxidation of the vitamin D₃ 4-phenyltriazoline-3,5-dione adducts 2 and 3 with MCPBA, four diastereomeric bisoxiranes 7, 8, 9, and 10 were generated.The stereochemistry of all the chiral centers in these compounds has been established by chemical correlation with compounds of known stereochemistry and by single crystal X-ray structure determination of the benzoyl derivative 10b. - Keywords.Vitamin D₃ 4-phenyl-triazoline-3,5-dione adducts, bisoxiranes of; Complete assignment of stereochemistry; Single crystal X-ray structure determination.