Journal of Medicinal Chemistry p. 42 - 50 (1983)
Update date:2022-08-04
Topics: Synthesis
Huegi, Bruno S.
Ebnoether, Anton M.
Rissi, Erwin
Gadient, Fulvio
Hauser, Daniel
et al.
A series of 4,4-disubstituted piperidines has been synthesized and evaluated for analgesic activity.Several of these analogues show analgesic potency comparable to morphine in the mouse writhing and tail-flick tests.A number of compounds exhibit high affi
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Doi:10.1016/S0022-328X(00)96088-1
(1982)Doi:10.1007/BF00513444
(1982)Doi:10.1002/jlac.198119810715
(1981)Doi:10.1016/S0040-4039(00)87595-4
(1982)Doi:10.1021/ja00349a011
(1983)Doi:10.1016/S0040-4039(00)96698-X
(1987)
