Journal of Medicinal Chemistry p. 1794 - 1798 (1987)
Update date:2022-09-26
Topics:
Campbell, Simon F.
Plews, Rhona M.
A series of 4-amino-6,7-dimethoxy-2-(4-heterocyclylpiperazin-1-yl)quinazolines (3) was prepared and screened for α-adrenoceptor affinity and antihypertensive activity.These quinazoline derivatives showed high binding affinity (ca. 10-10 M) and
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