Journal of Heterocyclic Chemistry p. 209 - 215 (1998)
Update date:2022-07-29
Topics:
Ibrahim, Alhussein A.
Matsumoto, Mutsumi
Miyahara, Yuji
Izumi, Kenji
Suenaga, Masahiko
Shimizu, Nobujiro
Inazu, Takahiko
A new series of macrocyclic compounds with one or two Troeger base skeletons has been synthesized by condensing mono-, di-, tri-, and teraethyleneglycol bis(p-aminophenoxy) ethers with formalin in the presence of concentrated hydrochloric acid in ethanol at room temperature for 13 days. This simple one-step cyclization provided 19 in remarkably high yield (46%) and 17, 18, and 20 in yields reflecting the strain of the rings and statistical factors. Complexation with lithium thiocyanate was observed for 20, the structure of which was elucidated by X-ray crystallography.
View MoreSuzhou SuKaiLu Chemical Technology Co., Ltd.
Contact:+86-512-62766020
Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Disynthesis Chemical Technology Co. Ltd.
Contact:+86-571-88194596
Address:Dengyun road 380, Gongshu district, Hangzhou city, China
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)
Contact:+86 021 50106671
Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park
Tianjin Realet Chemical Technology Co.,Ltd.
website:http://www.realetchem.com
Contact:+86-022-58788819
Address:shuanggang industrial park
Nanjing Qirui Material Co., Ltd.
Contact:+86-25-52320053
Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
Doi:10.1039/c7ob03081a
(2018)Doi:10.1021/jo00152a032
(1983)Doi:10.1016/S0014-827X(99)00118-4
(2000)Doi:10.1016/S0008-6215(00)80776-4
(1982)Doi:10.1002/jps.2600711105
(1982)Doi:10.1021/ja021224f
(2003)