Chiral Allenylboronic Esters as a Practical Reagent for Enantioselective Carbon-Carbon Bond Formation. Facile Synthesis of (-)-Ipsenol

Article abstract of DOI:10.1021/ja00263a020

A stereospecific synthetic route to (-)-ipsenol is described.The synthesis illustrates a new asymmetric synthetic reaction using chiral allenyl boronic esters.The scope of the synthesis as a general route to either (R)- or (S)-3-alkynol is further illustrated by several cases.