A New Synthetic Approach to the Carbapenem Antibiotic PS-5 from Ethyl (S)-3-Hydroxybutanoate

DOI: 10.1246/cl.1987.2187

Source and publish data:

Chemistry Letters p. 2187 - 2188 (1987)

Update date:2022-08-03

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Authors:

Chiba, Toshiyuki

Nakai, Takeshi

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Article abstract of DOI:10.1246/cl.1987.2187

A new synthetic route to the PS-5 key precursor is described which involves the fully stereocontrolled transformation of the optically active 2-azetidinone derivative easily obtainable from ethyl (S)-3-hydroxybutanoate.

Full text of DOI:10.1246/cl.1987.2187

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