A New Synthetic Approach to the Carbapenem Antibiotic PS-5 from Ethyl (S)-3-Hydroxybutanoate

DOI: 10.1246/cl.1987.2187

Source and publish data:

Chemistry Letters p. 2187 - 2188 (1987)

Update date:2022-08-03

Topics:

Authors:

Chiba, Toshiyuki

Nakai, Takeshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1987.2187

A new synthetic route to the PS-5 key precursor is described which involves the fully stereocontrolled transformation of the optically active 2-azetidinone derivative easily obtainable from ethyl (S)-3-hydroxybutanoate.

Full text of DOI:10.1246/cl.1987.2187

Products guided by the article

Product name:(5R,6R)-6-Ethyl-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester

Cas No:84048-08-8

R&D Labs maybe for 84048-08-8

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

website:http://www.bjgreenchem.com/

Contact:+86-427-6515887

Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Linyi VIHO Chemical Co.,Ltd

Contact:86-15588110016

Address:LINYI CITY,SHANDONG PROVINCE,CHINA
Ji'nan Orgachem Pharmaceutical Co.,Ltd

Contact:+86-531-82687810

Address:Jinan
Changzhou LanXu Chemical Co.,ltd.(expird)

Contact:86-0519-86330911,13656129734,15261186386

Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China

Relevant to this article

AMINO ACID DERIVATIVES THAT STABILIZE SECONDARY STRUCTURES OF POLYPEPTIDES. I. SYNTHESIS OF LL-3-AMINO-2-PIPERIDONE-6-CARBOXYLIC ACID (LL-Acp), A NOVEL BETA-TURN-FORMING AMINO ACID

Doi:10.1016/S0040-4039(00)87699-6
(1982)
Direct Preparation of α>-Diprotected L-α-Aminoadipic Acid from L-Lysine

Doi:10.1039/c39820000818
(1982)
Pinacol rearrangement of 3,4-dihydro-3,4-dihydroxyquinolin-2(1H)-ones: An alternative pathway to viridicatin alkaloids and their analogs

Doi:10.1002/hlca.201300074
(2013)
Transesterification of the α-keto ester in methyl pheophorbide-a

Doi:10.1016/0040-4039(96)01075-1
(1996)
Addition compounds of alkali-metal hydrides. 25. Rapid reaction of boronic esters and acids with lithium aluminum hydride. A novel and quantitative synthesis of lithium monoorganylborohydrides

Doi:10.1021/om00083a022
(1984)
Total synthesis of laulimalide: Synthesis of the northern and southern fragments

Doi:10.1002/chem.201102898
(2012)

Article Doi