Studies on 2-Aziridinecarboxylic Acid. VI. Synthesis of β-Alkoxy-α-Amino Acids via Ring-opening Reaction of Aziridine

DOI: 10.1246/bcsj.55.3049

Source and publish data:

Bulletin of the Chemical Society of Japan p. 3049 - 3050 (1982)

Update date:2022-09-26

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Authors:

Nakajima, Kiichiro

Neya, Masahiro

Yamada, Shinichi

Okawa, Kenji

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Article abstract of DOI:10.1246/bcsj.55.3049

The reaction of aziridine derivatives having a urethane-type protecting group with several alcohols in the presence of boron trifluoride etherate afford the corresponding optically pure O-alkylserine and O-alkylthreonine derivatives via a ring-opening reaction of aziridine in good yield.

Full text of DOI:10.1246/bcsj.55.3049

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