Design of peptides with α,β-dehydro-residues: Synthesis and crystal structure of a tetrapeptide Boc-Ala-ΔPhe-ΔPhe-Phe-OCH 3

Article abstract of DOI:10.1007/s10870-005-3884-y

In order to develop general rules of peptide design with α,β-dehydro-residues, a peptide, Boc-Ala-ΔPhe-ΔPhe-Phe- OCH₃, was synthesized. The peptide was crystallized from its solution in an acetone:water mixture (70:30). The crystals belong to o