Hydrozirconation of four-, five-, six- and seven-membered N-alkoxycarbonyl lactams to lactamols

DOI: 10.1016/j.tetlet.2011.10.006

Source and publish data:

Tetrahedron Letters p. 6880 - 6882 (2011)

Update date:2022-07-30

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Authors:

Piperno, Anna

Carnovale, Caterina

Giofr, Salvatore V.

Iannazzo, Daniela

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Article abstract of DOI:10.1016/j.tetlet.2011.10.006

A general, practical, and efficient reduction of four-, five-, six- and, seven-membered N-alkoxycarbonyl lactams to the aldehyde oxidation state is reported. The reduction methodology involves the hydrozirconation reaction by Cp₂Zr(H)Cl under m

Full text of DOI:10.1016/j.tetlet.2011.10.006

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