The synthesis of diaminopimelic acid containing peptidoglycan fragments using metathesis cross coupling

Article abstract of DOI:10.1016/j.tetlet.2005.01.062

Properly protected diaminopimelic acid (DAP), a component of peptidoglycan of Gram-negative bacteria, was prepared by a metathesis cross coupling between properly protected allyl and vinyl glycine derivatives using Grubb's second-generation catalyst follo