DNA-BLEOMYCIN INTERACTION NUCLEOTIDE SEQUENCE-SPECIFIC BINDING AND CLEAVAGE OF DNA BY BLEOMYCIN

DOI: 10.1016/0040-4020(84)85055-3

Source and publish data:

Tetrahedron p. 501 - 509 (1984)

Update date:2022-09-26

Topics: Cleavage Nucleotide Experimental Interaction Binding DNA BLEOMYCIN

Authors:

Umezawa, Hamao

Takita, Tomohisa

Sugiura, Yukio

Otsuka, Masami

Kobayashi, Susumu

Ohno, Masaji

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Article abstract of DOI:10.1016/0040-4020(84)85055-3

Biosynthetic intermediates and synthetic analogues of bleomycin (BLM) have been investigated for their metal binding, dioxygen activation, and DNA cleavage.Molecular O2 was activated by the Fe(II) complex of a synthetic model ligand.Nucleotide sequence sp

Full text of DOI:10.1016/0040-4020(84)85055-3

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