New functionalised hydroxymethyl ketones from the mild and chemoselective KMnO4 oxidation of chiral terminal olefins

Article abstract of DOI:10.1002/ejoc.200500737

Various terminal olefinic compounds are directly converted into the corresponding α-hydroxy ketones in good yields by potassium permanganate oxidation. The reaction is also highly chemoselective in the presence of differently protected hydroxy groups and