
Journal of Antibiotics p. 1485 - 1493 (1993)
Update date:2022-08-03
Topics:
Kato
Shindo
Yamagishi
Matsuoka
Kawai
Mochizuki
Phenazoviridin is a newly discovered free radical scavenger from microorganisms. It was isolated from the culture of Streptomyces sp. HR04. The structure of phenazoviridin was determined as 6-(3-methyl-2-butenyl)phenazine-1-carboxylic acid 6-deoxy-α-L-talopyranose ester on the basis of its spectroscopic and physico-chemical properties. The novel substance showed strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibited antihypoxic activity in mice.
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