Anomeric effect on kinetic acidity: Examples for the oxygen atom of ethers to accelerate abstraction of an α-hydrogen atom

Article abstract of DOI:10.1016/S0040-4039(00)79174-X

In contrast with general observation, two different types of experiments indicate that the abstraction of α-hydrogen atom of ether having proper conformation is slightly enhanced by the oxygen atom in line with our previous AM1 calculation.