3′-Immobilized probes with 2′-caps: Synthesis of oligonucleotides with 2′-N-methyl-2′-(anthraquinone carboxamido)uridine residues

Article abstract of DOI:10.1021/ol0502432

(Chemical Equation Presented) A synthesis for oligodeoxynucleotides with a 3′-terminal 2′-N-methyl-2′-acylamido-2′-deoxyuridine residue was developed. Unlike their unmethylated counterparts, these oligodeoxynucleotides can be stably immobilized on aldehyd