Journal of Organic Chemistry p. 1769 - 1772 (1983)
Update date:2022-08-04
Topics:
Keinan, Ehud
Roth, Zeev
A new model for the characterization of nucleophiles is proposed, based on the regioselectivity of the reaction of a given nucleophile with 3-acetoxy-3-cyano-1-phenylpropene (14) in the presence of Pd(0) catalyst.A general correlation between regioselectivity using this indicator substrate and literature data on stereospecificity of nucleophilic substitution in other model compounds is apparent.
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(1967)
