Synthesis and Antiarrhythmic and Parasympatholytic Properties of Substituted Phenols. 1. Heteroarylamine Derivatives

DOI: 10.1021/jm00360a005

Source and publish data:

Journal of Medicinal Chemistry p. 808 - 813 (1983)

Update date:2022-07-30

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Authors:

Stout, David M.

Matier, W. L.

Barcelon-Yang, Cynthia

Reynolds, Robert D.

Brown, Barry S.

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Article abstract of DOI:10.1021/jm00360a005

Twenty-four structural derivatives of the antiarrhythmic drug changrolin were synthesized and tested for antiarrhythmic and parasympatholytic activities.It was found that while the bis(pyrrolidinylmethyl)phenol pattern of changrolin appeared to be optimal

Full text of DOI:10.1021/jm00360a005

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