SILICON IN BENZAMIDE DIRECTED ORTHO METALATION REACTIONS. CARBO- AND BROMO-DESILYLATIONS AND SYNTHESIS OF NATURALLY-OCCURING ANTHRAQUINONES

Article abstract of DOI:10.1016/S0040-4039(00)99917-9

Silylated benzamides 2, avaible by directed ortho metalation, undergo fluorideinduced carbodesilylation and ipso bromodesilylation to give usefully-substituted aromatics 3 and 4; these reactions are utilized in a short and efficient synthesis of erythrola