Silicon-directed stereocontrolled cyclization. Possible route to functionalized tetrahydrofurans

Article abstract of DOI:10.1016/S0040-4039(00)79973-4

Cyclization of 3,4,6-tri-O-benzyl-1-deoxy-1-phenyldimethylsilyl-L-glucitol using a slight excess of BF₃Et₂O or a catalytic amount of H₂SO₄ gives access to the 2,5-anhydro-L-glucitol or 2,5-anhydro-L-mannitol der