Stereoselective Synthesis of a (5R,6S)-6--2-aryloxypenem

DOI: 10.1039/c39830001005

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1005 - 1006 (1983)

Update date:2022-08-03

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Authors:

Cooke, Michael D.

Moore, Kevin W.

Ross, Barry C.

Turner, Susan E.

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Article abstract of DOI:10.1039/c39830001005

(5R,6S)-<(R)-1-Hydroxyethyl>-2-aryloxypenems can be synthesised through hydroxy group directed chlorinolysis of the (3S,4R)-3-<(R)-1-hydroxyethyl>-4-ethylthioazetidinone (8) to the (4S)-4-chloroazetidinone (9) with subsequent cyclisation.

Full text of DOI:10.1039/c39830001005

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