Journal of medicinal chemistry p. 1116 - 1122 (1983)
Update date:2022-08-05
Topics:
Watthey
Gavin
Desai
Finn
Rodebaugh
Patt
The synthesis of two thiophene-containing analogues of mianserin, i.e., 1,2,3,4,10,13b-hexahydro-2-methylpiperazino[1,2-a]thieno[2, 3-c][1]benzazepine (2), and the corresponding [3,2-c] isomer (12) is described. The key step in the synthesis is the nucleo
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