
Journal of Medicinal Chemistry p. 1164 - 1168 (1983)
Update date:2022-09-26
Topics:
Nair, M. G.
Salter, Otha C.
Kisliuk, Roy L.
Gaumont, Y.
North, G.
Two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system have been synthesized and evaluated for their antifolate activities.These compounds, N-<(2-amino-4-hydroxy-7,8-dihydro-8-oxa-6-pteridinyl)benzoyl>-L-glutamic acid (3) and
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Doi:10.1016/S0040-4039(00)81355-6
(1983)Doi:10.1021/jo071036d
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(1937)Doi:10.1039/jr9490000287
(1949)