Aza Analogues of Lucanthone: Synthesis and Antitumor and Bactericidal Properties

DOI: 10.1021/jm00363a022

Source and publish data:

Journal of Medicinal Chemistry p. 1329 - 1333 (1983)

Update date:2022-09-26

Topics:

Authors:

Croisy-Delcey, Martine

Bisagni, Emile

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00363a022

Three types of aza analogues of lucanthone were synthesized for evaluation as antitumor drugs.None of the compounds was found to have significant cytotoxic effects either on Friend tumor cells or on L1210 leukemia cells.However, one of the target compound

Full text of DOI:10.1021/jm00363a022

Products guided by the article

Product name:ethyl 1,2-dihydro-2-oxo-4-chloro-6-methylpyridine-3-carboxylate

Cas No:86129-62-6

R&D Labs maybe for 86129-62-6

Tianjin Realet Chemical Technology Co.,Ltd.

website:http://www.realetchem.com

Contact:+86-022-58788819

Address:shuanggang industrial park
Rayfull Holding Co., Ltd

Contact:+86-577-65618087-605

Address:Room 402, Unit 4 Xinhu Bldg. Waitan Ruian City, Zhejiang China.
Luojiang Chenming Biological Products Co

Contact:+86 15000297032

Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)

Contact:+86 021 50106671

Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park
Chengdu Yunyi International Trade Co., Ltd

Contact:

Address:china

Relevant to this article

1-(2-Pyridinyl)piperazine Derivatives with Antianaphylactic, Antibronchospastic, and Mast Cell Stabilizing Activities

Doi:10.1021/jm00384a002
(1987)
Aqueous enantioselective organocatalytic Diels-Alder reactions employing hydrazide catalysts. A new scaffold for organic acceleration

Doi:10.1021/ol051476w
(2005)
Rearrangement Studies on S-Propargyl-N-azacycloalkyl Acetals: Synthesis of Novel 3-Aroyl-2-(N-azacycloalkyl)-4-methylthiophenes

Doi:10.1055/s-1983-30359
(1983)
SYNTHESE ET ETUDE SPECTRALE UV DE CHAINES POLYMETALLEES (Ge, Si); ANALYSE THEORIQUE DES EFFETS DE SUBSTITUTION

Doi:10.1016/S0022-328X(00)98750-3
(1983)
Chemoenzymatic synthesis of calcilytic agent NPS-2143 employing a lipase-mediated resolution protocol

Doi:10.1016/j.tetasy.2005.07.022
(2005)
Formal alkyne insertion into alkoxycarbene complexes: Simple access to enantiopure group 6 alkynyl(alkoxy)carbene complexes

Doi:10.1002/anie.200501400
(2005)

Article Doi