Bioorganic and Medicinal Chemistry Letters p. 3296 - 3301 (2005)
Update date:2022-08-05
Topics:
Biftu, Tesfaye
Feng, Dennis
Ponpipom, Mitree
Girotra, Narindar
Liang, Gui-Bai
Qian, Xiaoxia
Bugianesi, Robert
Simeone, Joseph
Chang, Linda
Gurnett, Anne
Liberator, Paul
Dulski, Paula
Leavitt, Penny Sue
Crumley, Tami
Misura, Andrew
Murphy, Terence
Rattray, Sandra
Samaras, Samantha
Tamas, Tamas
Mathew, John
Brown, Christine
Thompson, Don
Schmatz, Dennis
Fisher, Michael
Wyvratt, Matthew
Several analogs of 2,3-diaryl pyrroles were synthesized and evaluated as inhibitors of Eimeria tenella cGMP-dependent protein kinase and in in vivo anticoccidial assays. A 4-fluorophenyl group enhances both in vitro and in vivo activities. The most potent
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