Synthesis and antitumor activity of 7- and 9-(6'-deoxy-α-L-talofuranosyl)hypoxanthine and 9-(6'-deoxy-α-L-talofuranosyl)-6-thiopurine

Article abstract of DOI:10.1021/jm00364a032

Reaction of 6-deoxy-2,3,5-tris-O-(p-nitrobenzoyl)-L-talofuranosyl bromide (I) with the trimethylsilyl derivative of hypoxanthine, followed by removal of blocking groups, afforded 9- (6) and 7-(6'-deoxy-α-L-talofuranosyl)hypoxanthine (7). A study of the pu