
Canadian Journal of Chemistry p. 1880 - 1888 (1996)
Update date:2022-08-04
Hanessian, Stephen
Ninkovic, Sacha
The lactone portion of the podophylotoxin framework was assembled from a free-radical carbocyclization reaction, and the target structure was constructed based on intramolecular Friedel-Crafts reaction. In addition to isodeoxypodophyllotoxin, there were formed unusual tri- and tetracyclic compounds.The lactone portion of the podophylotoxin framework was assembled from a free-radical carbocyclization reaction, and the target structure was constructed based on intramolecular Friedel-Crafts reaction. In addition to isodeoxypodophyllotoxin, there were formed unusual tri- and tetracyclic compounds.
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