Tetrahedron Letters p. 2323 - 2326 (1983)
Update date:2022-07-30
Topics:
Manhas, M.S.
Khajavi, M.S.
Bari, S.S.
Bose, Ajay K.
A convenient synthesis of 3,3-dibromo-2-azetidinones involves the reaction of an imine with the trimethylsilyl ester of tribromoacetic acid and triphenylphosphine; reduction with n-Bu3SnH and n-Bu3SnD can be controlled to lead to cis-3-bromo-2-azetidinones, and cis or trans 3-deuterio-2-azetidinones.
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Doi:10.1021/ja403813b
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