
Chemistry of Heterocyclic Compounds p. 630 - 634 (1983)
Update date:2022-08-04
Topics:
Petrulyanis, L. N.
Veinberg, G. A.
Kononov, L. I.
Dipan, I. V.
Lukevits, E. Ya.
6-Ureido and 6-thioureidopenicillanic acids and 7-ureido- and 7-thioureidodeacetoxycephalosporanic acids were obtained by the reaction of 6-aminopenicillanic acid and 7-aminodeacetoxycephalosporanic acids with tetraisocyanatosilane or tetraisothiocyanatosilane.N-Carbamoyl derivatives of ureido- and thioureidopenicillanic acids were isolated after repeated treatment of 6-ureido- and 6-thioureidopenicillanic acids with the indicated isocyanatosilanes.
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