Bioorganic and Medicinal Chemistry p. 1022 - 1029 (2017)
Update date:2022-08-03
Topics:
Pervez, Humayun
Khan, Nazia
Zaib, Sumera
Yaqub, Muhammad
Naseer, Muhammad Moazzam
Tahir, Muhammad Nawaz
Iqbal, Jamshed
A series of fifteen N4-benzyl substituted 5-nitroisatin-3-thiosemicarbazones 5a–o was synthesized and evaluated for urease inhibitory, phytotoxic and cytotoxic influences. All the compounds proved to be highly potent inhibitors of the enzyme, s
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