Synthesis of the metabolites of afloqualone and related compounds

DOI: 10.1248/cpb.31.1158

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1158 - 1165 (1983)

Update date:2022-08-05

Topics:

Authors:

Yamada Yamada

Otsuka Otsuka

Tani Tani

Oine Oine

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.31.1158

Seven main metabolites (3-9) of afloqualone (1, 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazoline and related 4(3H)-quinazolinone derivatives were synthesized. The metabolites 4 and 5 containing a sulfur atom were prepared by the reaction of 6-acetamid

Full text of DOI:10.1248/cpb.31.1158

NII-Electronic Library Service

Products guided by the article

Product name:2-fluoromethyl-6-hydroxyamino-3-(o-hydroxymethylphenyl)-4(3H)-quinazolinone

Cas No:87266-15-7

R&D Labs maybe for 87266-15-7

Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

website:http://www.czyys.com

Contact:0086-519-88802789

Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
Alway Chem, China

website:http://www.alwaychem.com

Contact:+86-532-8586-4000, 8586-5000

Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
Shanghai Cheerchem Co., Ltd.

Contact:86-21-50966856

Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai

Relevant to this article

N -heterocyclic carbene-catalyzed internal redox reaction of alkynals: An efficient synthesis of allenoates

Doi:10.1021/ol300111m
(2012)
Solution-phase synthesis of branched DNA hybrids based on dimer phosphoramidites and phenolic or nucleosidic cores

Doi:10.1021/jo202505h
(2012)
Unsymmetrically substituted 9,10-dihydro-9,10-diboraanthracenes as versatile building blocks for boron-doped π-conjugated systems

Doi:10.1002/chem.201101701
(2011)
A palladium-catalyzed three-component reaction for the preparation of quinazolin-4(3H)-imines

Doi:10.1039/c2cc18001d
(2012)
The inhibition of liposaccharide heptosyltransferase WaaC with multivalent glycosylated fullerenes: A new mode of glycosyltransferase inhibition

Doi:10.1002/chem.201102052
(2012)
Copper ion mediated selective cleavage of C-S bond in ferrocenylthiosemicarbazone forming mixed geometrical [(PPh₃)Cu(μ- S)₂Cu(PPh₃)₂] having Cu₂S ₂ core: Toward a new avenue in copper-sulfur chemistry

Doi:10.1021/ic2022616
(2012)

Article Doi