Synthesis of the metabolites of afloqualone and related compounds

DOI: 10.1248/cpb.31.1158

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1158 - 1165 (1983)

Update date:2022-08-05

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Authors:

Yamada Yamada

Otsuka Otsuka

Tani Tani

Oine Oine

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Article abstract of DOI:10.1248/cpb.31.1158

Seven main metabolites (3-9) of afloqualone (1, 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazoline and related 4(3H)-quinazolinone derivatives were synthesized. The metabolites 4 and 5 containing a sulfur atom were prepared by the reaction of 6-acetamid

Full text of DOI:10.1248/cpb.31.1158

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