
Chemical and Pharmaceutical Bulletin p. 189 - 192 (1995)
Update date:2022-08-03
Topics:
Ando
Koike
Takayama
An improved synthesis of a highly potent vitamin D3 analog, 24,24-difluoro-1α,25-dihydroxyvitamin D3 (1b) has been accomplished via vitamin D2-SO2 adducts. The introduction of fluorine atoms was performed by tre
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