Journal of Organic Chemistry p. 505 - 507 (1986)
Update date:2022-08-05
Topics:
Lazzaroni, Raffaello
Pini, Dario
Bertozzi, Sergio
Fatti, Graziella
The addition of the butenyl Grignard reagent to the unactivated double bond of 2-(α-methylallylic) aza aromatic compounds is completely regioselective giving the 2-(1,4-dimethyl-5 hexen-1-yl) aza aromatics in good yield.A preliminary coordination of magnesium atom to nitrogen atom and the formation of a six-center transition state involving the butenyl Grignard and the vinyl group has been proposed in order to explain the selectivity of the reaction.
View MoreHangzhou Neway Chemicals Co., Ltd.
Contact:+86-571-85095566
Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
FREEBARQUE DEVELOPMENT GROUP LIMITED
Contact:+86(0)10-5109 5335 or 5109 5345
Address:Room602,Block1-B,LINGDI OFFICE,NO.13 BEIYUAN ROAD
Dalian Synco Chemical Co., Ltd.
Contact:+86-411-83635150
Address:Rm 1004, 24, Tangshan Street, Dalian
Jiangsu Zenji Pharmaceuticals LTD
Contact:+86-025-83172562; +1-224-888-1133(USA)
Address:No.5 Xinmofan Road
Pengchen New Material Technology Co., Ltd.
Contact:+86-512-63680537
Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Doi:10.1021/jm8008508
(2008)Doi:10.1016/S0022-328X(00)99234-9
(1983)Doi:10.1002/jhet.5570430105
(2006)Doi:10.1021/ic0512983
(2006)Doi:10.1021/ja056318e
(2006)Doi:10.1021/jo00070a004
(1993)
