Renin inhibitors. Statine-containing tetrapeptides with varied hydrophobic carboxy termini

Article abstract of DOI:10.1021/jm00393a029

A series of statine-containing tetrapeptides, systematically modified at the carboxy terminus with various hydrophobic aromatic groups, is described. These compounds were tested in vitro for their ability to inhibit porcine, human plasma, and purified hum