Design, synthesis, and X-ray data of novel potential antipsychotic agents. Substituted 7-phenylquinolizidines: stereospecific, neuroleptic and antinociceptive properties

DOI: 10.1021/jm00368a011

Source and publish data:

Journal of Medicinal Chemistry p. 165 - 175 (1984)

Update date:2022-07-30

Topics: Synthesis Novel Design Stereospecific Neuroleptic

Authors:

Imhof Imhof

Kyburz Kyburz

Daly Daly

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00368a011

The semirigid 7-phenylquinolizidine system was selected for the design of new potential antipsychotic agents because it fulfills earlier considerations on the minimal structural and steric requirements necessary to attain a high affinity to the dopamine r

Full text of DOI:10.1021/jm00368a011

Products guided by the article

Product name:Pyridine, 6-ethoxy-2,3,4,5-tetrahydro-3-[4-(trifluoromethyl)phenyl]-

Cas No:87922-82-5

R&D Labs maybe for 87922-82-5

Amadis Chemical Co., Ltd.

website:http://www.amadischem.com

Contact:86-571-89925085

Address:Watts Cosine.No.166.Xiangmao Road.
Jinan Baozhao Pharmaceutical Co., Ltd

Contact:0086-531-86397156 82371858 82371868

Address:Huaneng Road, Jinan, Shandong ,China
Fusilin chemical science & technology co., ltd.

Contact:532-80698166/86057573, +86-400-669-7885

Address:School of Material Science & Engineering, Shandong Uinversity of Science & Technology, Huangdao Zone, Qindao, Shandong
Hebei Fulong Import & Export Co., Ltd.

Contact:86-311-87795661

Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Richest Group Ltd.

Contact:+86 21 5017 5386

Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China

Relevant to this article

Practical formal total syntheses of the homocamptothecin derivative and anticancer agent diflomotecan via asymmetric acetate aldol additions to pyridine ketone substrates

Doi:10.1021/jo060928v
(2006)
REACTION OF 1-HALO-3-METHYL-2,3-EPOXYBUTANES WITH SECONDARY AMINES

Doi:10.1007/BF00506872
(1983)
Synthesis and electrochemical and spectroscopic properties of molybdenum complexes bearing 5-alkoxythiophene or -bithiophene groups

Doi:10.1002/ejic.200401012
(2005)
A glycal approach towards an efficient and stereodivergent synthesis of polyhydroxypyrrolidines

Doi:10.1016/j.tet.2005.11.037
(2006)
Synthesis of Pyridines, Quinolines, and Pyrimidines via Acceptorless Dehydrogenative Coupling Catalyzed by a Simple Bidentate P^ N Ligand Supported Ru Complex

Doi:10.1021/acs.organomet.0c00058
(2020)
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119): A Cytotoxic Prodrug with Two Stable Conformations Differing in Biological and Physical Properties

Doi:10.1111/j.1747-0285.2011.01193.x
(2011)

Article Doi