Design, synthesis, and X-ray data of novel potential antipsychotic agents. Substituted 7-phenylquinolizidines: stereospecific, neuroleptic and antinociceptive properties

DOI: 10.1021/jm00368a011

Source and publish data:

Journal of Medicinal Chemistry p. 165 - 175 (1984)

Update date:2022-07-30

Topics: Synthesis Novel Design Stereospecific Neuroleptic

Authors:

Imhof Imhof

Kyburz Kyburz

Daly Daly

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Article abstract of DOI:10.1021/jm00368a011

The semirigid 7-phenylquinolizidine system was selected for the design of new potential antipsychotic agents because it fulfills earlier considerations on the minimal structural and steric requirements necessary to attain a high affinity to the dopamine r

Full text of DOI:10.1021/jm00368a011

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