SYNTHETIC APPROACH TOWARD MITOMYCINS. SYNTHESIS OF 9-BENZYLOXYMETHYL-5-METHOXY-4-METHYL-3H-PYRROLOINDOL-4,5-DIONE

Article abstract of DOI:10.1246/cl.1983.1383

2-Azido-3-(1'-benzyloxymethyl-2',4'-pentadienyl)-5-methoxy-6-methyl-1,4-benzoquinone is prepared and its thermal decomposition under the presence of Cu(acac)2 affords the corresponding 3H-pyrrolo<1,2-a>indol-5,8-dione, which is the important precursor for