Chemistry - A European Journal p. 1174 - 1184 (2006)
Update date:2022-08-04
Topics:
Bughin, Carine
Zhao, Gang
Bienayme, Hugues
Zhu, Jieping
A conceptually novel macrolactonization protocol has been developed. It is a domino process involving a sequence of: 1) protonation of 5-aminooxazole leading to the electrophilic iminium salt; 2) trapping of the iminium species by the neighboring C-termin
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