Synthesis of 1,2,3,4-tetrahydroquinazoline derivatives as potential alpha-adrenergic blocking agents

Article abstract of DOI:10.1002/jhet.5570200525

The synthesis of N,N'-bis[6-(1,2,3,4-tetrahydro-3-quinazolidyl)hexyl)cystamine (1) and 3-(6-aminohexyl)-1,2,3,4-tetrahydroquinazoline (II) are described. Compound I is obtained by condensation of o-nitrobenzoyl chloride with 3-(6-aminohexyl)-1,3-thiazolid